Ketamine modulates fetal hemodynamic and endocrine responses to umbilical cord occlusion
نویسندگان
چکیده
منابع مشابه
Ketamine modulates fetal hemodynamic and endocrine responses to umbilical cord occlusion
Umbilical cord occlusion (UCO) is a hypoxic insult that has been used to model birth asphyxia and umbilical cord compression in utero. UCO triggers vigorous neural and endocrine responses that include increased plasma ACTH and cortisol concentrations, increased blood pressure (BP), and decreased heart rate (HR). We have previously reported that ketamine, a noncompetitive N-methyl-D-aspartate re...
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Fetal acidemia during labor is associated with an increased risk of brain injury and lasting neurological deficits. This is in part due to the repetitive occlusions of the umbilical cord (UCO) induced by uterine contractions. Whereas fetal heart rate (FHR) monitoring is widely used clinically, it fails to detect fetal acidemia. Hence, new approaches are needed for early detection of fetal acide...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2016
ISSN: 2051-817X
DOI: 10.14814/phy2.12962